Isaac's Dice Room: The Most Powerful Item Combinations - OpenSIPS Trunking Solutions

(rerolls all held items, pickups, trinkets, and pedestal items)

Just curious, what are some of the better item combinations you've come across in your runs? Read also: FakeHub The Wish Makers: Your Questions Answered (Finally!)

Haemolacria + brimstone + tech x + polyphemus + dead eye + 20/20 + ipecac.

I don't remember all the items, but i got pretty lucky by getting two small rooms in the womb with spiked floor, two item pedestals, and a reroll machine. Read also: 5 Things You Didn't Know About This Knoxville Craigslist Find

It was the sickest combo i've ever had. Read also: Craigslist Lincoln Listing: The Clues You've Been Missing

Wish i remembered all the items tho.

Has anyone gotten some insanely strong item combinations so far?

1) the ludovico technique + technology this creates a pretty large, controllable laser circle on the ground. Read also: What Top Scientists Say About The EMF-CNF Connection And Your Risk

Anything that touches this, recieves damage multiple times per second.

Bosses died within a few seconds.

2) tammys head + brimstone this really takes the cake.

Dice rooms are special rooms that can randomize many elements of the run.

Dice rooms require two keys to be opened, unlike most other special rooms.

For a dice room to spawn, two things must happen;

First, the game must decide that a sacrifice room will spawn that floor.

The dice room in the binding of isaac:

Repentance is a notoriously unpredictable yet potentially rewarding challenge.

This enigmatic room offers a gamble:

The chance to drastically improve your run with powerful item combinations, or to plummet into despair with cripplingly negative effects.

On any red heart character it would probably be rock bottom > kidney stone > pyromaniac > ipecac.

After that you could always go for item buff such as spindown dice > glitched crown, which is basically a way better death certificate.